%0 Journal Article %A Spencer Carson and Meni Wanunu %D 2015 %J Nanotechnology %N 7 %V 26 %P 074004 %T Challenges in DNA motion control and sequence readout using nanopore devices %U http://stacks.iop.org/0957-4484/26/i=7/a=074004 %X Nanopores are being hailed as a potential next-generation DNA sequencer that could provide cheap, high-throughput DNA analysis. In this review we present a detailed summary of the various sensing techniques being investigated for use in DNA sequencing and mapping applications. A crucial impasse to the success of nanopores as a reliable DNA analysis tool is the fast and stochastic nature of DNA translocation. We discuss the incorporation of biological motors to step DNA through a pore base-by-base, as well as the many experimental modifications attempted for the purpose of slowing and controlling DNA transport. %@ 0957-4484